Job Description

Reference No. R2662585

Position Title: Technologist

Duration: Fixed-Term - Contract End Date: December 22, 2023

Department: Immunochemistry

Location: Sanofi Pasteur Limited, Toronto, Ontario

Sanofi Pasteur: The world's leading vaccine company

Sanofi Pasteur, the vaccines division of Sanofi, is the largest company in the world devoted entirely to human vaccines. Our driving goal is to protect people from infectious diseases by creating safe and effective vaccines. Our company distributes more than 1 billion doses of vaccine each year, making it possible to vaccinate more than 500 million people across the globe. Sanofi Pasteur offers the broadest range of vaccines in the world, providing protection against 20 bacterial and viral diseases.

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

Major Activities of the Job:

Coordinates and performs routine standard testing:

Responsible for coordinating and performing assigned routine immunochemical and instrumental assays within a team environment in accordance with existing SOPs (e.g. ELISAs, cell-based assays, SDS-PAGE/Densitometry, identity by Western Blot/Dot Blot/LC-MS/FTIR; HPLC, IC, GC, UV-VIS,TOC, Osmometry).

Responsible for daily maintenance of test related equipment and system suitability, as required. Ensures that cleaning procedures, calibration and or validation of equipment meets testing requirements, alerts others if issues arise. (ELISA plate washers/ readers, LC-MS and Chromatography systems, Densitometer, UV-VIS, FTIR, Biosafety cabinets, pipettes, balances, pH and Conductivity meters and weight sets.).

Responsible for coordinating and performing routine in-house wet chemistry tests on in-process materials or final products (e.g. Nitrogen determination by micro-Kjeldahl, Aluminum by complexometric titration, identity by TLC)

Documentation - Testing and Support Documents:

Responsible for the timely and accurate completion and verification oftest related documents to ensure on time delivery of test results. (e.g. data in LIMS, worksheets, log books, test requisitions, verification of calculations for accuracy, verification of entries and transcription of data, review of electronic data including audit trails, as applicable).

Manage samples outsourced to approved contract labs including documentation preparation (Test Request and Shipping Form), review of test results (Certificates) from contract labs and transcription ofresults into LIMS or internal QC release documents, as required.

Responsible for ensuring testing SOPs are accurate and reflect current testing procedures.

Maintenance of Quality Systems including adherence to GXPs and safety guidelines:

Ensures compliance is maintained in all daily activities by following SOPs (divisional, department & test), protocols and procedures as they apply. Reviews SOPs on an annual basis, documents training.

Ensures that own training and qualification as per the qualification plan is current, with no overdue training.

Responsible for identifying and notifying Manager of any laboratory non. conformances (deviations). Initiates LIRs and contributes to laboratory investigations and deviation reports as required, provides required documentation support to expedite closures of deviations. Participates in root cause analysis to identify appropriate corrective actions for CAPA and events.

General Maintenance of Work Area, Test Related Equipment, Chemicals, Reagents and Lab Supplies:

Responsible for general maintenance of work area including cleaning of lab benches and all work surfaces, equipment maintenance and disposal of biohazardous waste and chemical waste.

Responsible for performing and completing the assigned lab duties in a timely manner.

Maintain general lab equipment (e.g. balances, fridges, freezers, water purification systems) and perform routine calibration checks, cleaning and preventative maintenance as required. Ensure the operation of equipment is satisfactory.

Test Transfer, Validation, & Implementation, Continuous Improvement:

Participates in projects for existing products and new products (e.g. collaborative studies with regulatory agencies and organizations on method comparison, assay/specification harmonization, new assay development, stability studies). Attend team meetings providing technical expertise on respective assays as required.

Responsible for writing protocols and reports for test transfer and method validation as required.

Execute studies under approved protocols for test transfer and new method validations, existing method revalidation.

Training/Skills Upgrade/Literature Review:

Complete On-the-job training according to current Lesson plans, and document as required.

Participate in regularly scheduled GMP updates and safety training.

Complete the relevant and required tests and trainings on site procedures, USP, EP, ACS, etc. as required.

Assist in training of new staff or existing personnel as required.

Minimum Qualifications:

Minimum four (4) year Bachelor's Degree (Chemistry, Biochemistry, Immunology, Biomedical Sciences or Molecular Biology).

Preferred two (2) years Master's Degree (Chemistry, Biochemistry, Immunology, Biomedical Sciences or Molecular Biology), plus a minimum of eighteen (18) months of previous relevant work experience.

Standard Analytical Lab Techniques (accurate transfer of weighed material, accurate volumetric measurement).

Sound Knowledge and Practical Expertise in Immunochemical Assavs and Chemical/Biochemical Assays.

Sound knowledge of GMP requirements, including GDP.

Asceptic Cell Culture Techniques.

Theoretical & Research related knowledge in Chemistry/Biochemistry, Immunology, Cell Biology.

Well-developed Computer Skills

Excellent Communication skills

Detail-oriented individual

Ability to work independently and within a team setting

Hours Of Work:

Inclusive from Monday to Friday: 8:00 a.m. - 4:00 p.m.

Sanofi is an equal opportunity employer committed to diversity and inclusion. Our goal is to attract, develop and retain highly talented employees from diverse backgrounds, allowing us to benefit from a wide variety of experiences and perspectives. We welcome and encourage applications from all qualified applicants. Accommodations for persons with disabilities required during the recruitment process are available upon request.

Thank you in advance for your interest.

Only those candidates selected for interviews will be contacted.

Sanofi, Empowering Life

#GD-SP #LI-SP

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.