Job Description

Reference No. R2646332






Position Title: Technologist Department: DP Unit NA 2 Duration: Full-Time Permanent Location: Sanofi Pasteur Limited, Toronto, Ontario Sanofi Pasteur: The world’s leading vaccine company Sanofi Pasteur, the vaccines division of Sanofi, is the largest company in the world devoted entirely to human vaccines. Our driving goal is to protect people from infectious diseases by creating safe and effective vaccines. Our company distributes more than 1 billion doses of vaccine each year, making it possible to vaccinate more than 500 million people across the globe. Sanofi Pasteur offers the broadest range of vaccines in the world, providing protection against 20 bacterial and viral diseases. Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Major Activities of the Job Develop, implement and execute immunochemical assays such as ELISA, surface plasmon resonance, immuno-chemioluminescence, radial immunodiffusion, immunoblotting, etc. under minimum supervision. Coordination and execution of animal immunogenicity studies to support formulation development and stability studies.

• Design and execute formulation and stability testing for viral and bacterial antigens for process development and improvement.
• Experiments require knowledge of immunochemical methods, protein characterization, wet chemistry, computerized instrumentation and aseptic technique.
• Collaborate with members of BAD, ARD and QC in order to co-ordinate experiments, testing, and troubleshooting.
• Organize and schedule experiments in order to ensure that work is timely and efficiently performed.
• Maintain accurate records of all experimental data.

Perform analytical and bioanalytical techniques such as HPLC, UV-Vis and fluorescence spectroscopy, dynamic light scattering, isothermal titration calorimetry, plaque assays, for in- process monitoring and formulation of liquid and freeze-dried products.

• Coordinate ongoing stability studies to ensure that materials are distributed, tests are performed, and data is entered correctly.
• Design and coordinate new stability studies.

Coordinate Development stability studies. May be asked to participate on working groups, task forces, teams, etc. for consistency across Development.

• Coordinate ongoing stability studies to ensure that materials are distributed, tests are performed, and data is entered correctly.
• Design and coordinate new stability studies.

Preparation of interim formulation reports, methods, SWis, SOPs and BPRs.

• Prepare reports summarizing experimental and assay results to be disseminated to supervisor and external customers.
• Write new experimental and assay methods as they are developed.
• Write, edit and review SOPs and BPRs.

Perform compliantly with employment and health & safety legislation and work within the policies, procedures and regulations.

• Takes every reasonable precaution to ensure the health and safety for self and co- workers.
• Uses required protective equipment and clothing
• Reports critical incidents and accidents to the appropriate authorities.
• Participates in the investigation of incidents and work related illnesses.
• Responds promptly to all health and safety concerns or incidents and completes the appropriate documentation in a timely manner.
• Cooperates and assists the Joint Health and Safety Committee that is carrying out its functions.
• Participates and contributes to the PASS objectives.

Minimum Qualifications

• Minimum four (4) years Bachelor of Science in Biochemistry, Molecular Biology, Immunology plus a minimum of one (1) year of previous relevant work experience.
• Preferred three (3) years of Masters in Biochemistry, Biotechnology, Biology, Immunology plus a minimum of six (6) months previous relevant work experience.
• Knowledge of animalimmunogenicity protocols and reports generation.
• Strong knowledge and familiarity with Aseptic techniques, and cGMP, cGLP practices.
• Strong mathematical skills, data analysis and analytical skills in determining protein content, concentration, assay development of immunochemicaltechniques and testing serum antibody titers.
• Basic computer skills in MS Word, Excel, SAP.

Hours Of Work

• Inclusive from Monday – Friday: 8:00 a.m. – 4:00 p.m.

Sanofi is an equal opportunity employer committed to diversity and inclusion. Our goal is to attract, develop and retain highly talented employees from diverse backgrounds, allowing us to benefit from a wide variety of experiences and perspectives. We welcome and encourage applications from all qualified applicants. Accommodations for persons with disabilities required during the recruitment process are available upon request. Thank you in advance for your interest. Only those candidates selected for interviews will be contacted. Sanofi, Empowering Life #GD-SP #LI-SP At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.