Senior Scientist, Radiochemist

Toronto, ON, Canada

Job Description


At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We\xe2\x80\x99re looking for people who are determined to make life better for people around the world.About POINT Biopharma:POINT Biopharma Global Inc. is a globally focused radiopharmaceutical company building a platform for the clinical development and commercialization of radioligands that fight cancer. Recently acquired by Eli Lilly and Company, POINT aims to transform precision oncology by combining a portfolio of targeted radioligand assets, a seasoned management team, an industry-leading pipeline, in-house manufacturing capabilities, and secured supply for medical isotopes including actinium-225 and lutetium-177. POINT is a wholly owned subsidiary of Eli Lilly and Company.Position Summary:The Radiochemist will be a technical expert in the discovery and development of radiolabeling reactions to produce both therapeutic and imaging radiopharmaceuticals. They will work in collaboration with team members, other departments, and external partners (CMOs) to ensure the successful development of novel radioligands, enable the supply of radiolabeled compounds for preclinical experiments, and support the development of radiopharmaceutical manufacturing processes for clinical development.Roles and Responsibilities of the Position:

  • Accelerate the development of the next-generation of radiopharmaceuticals by leading radiochemistry research and development for discovery programs.
  • Produce and supply radiolabeled compounds to support the preclinical evaluation of novel radioligands.
  • Support the development of cGMP radiopharmaceutical manufacturing processes to enable clinical development activities.
  • Develop new radiolabeling methods and formulations for discovery and preclinical stage programs.
  • Synthesize, test, and supply radiolabeled compounds for preclinical experiments
  • Provide technical support for the development of cGMP radiopharmaceutical manufacturing processes.
  • Prepare and deliver presentations for internal and external team meetings.
  • Author development reports, manuscripts for publication in journals, and patents.
Required Qualifications:
  • PhD or MS degree in radiochemistry, organic chemistry, chemical engineering, or a related discipline.
  • 5 to 10 years of relevant experience in radiochemistry, radiopharmaceutical manufacturing, organic chemistry, or process chemistry.
  • Proven ability to work independently with strong organization and communication skills.
  • Demonstrated ability to successfully prioritize projects and manage timelines in a fast-paced environment.
  • Functional knowledge of GMPs and applicable FDA, EMA, Health Canada, USP, ICH and PDA guidelines.
Additional Preferences:
  • Experienced in radiochemistry development. Hands-on experience with imaging radioisotopes (F-18, Ga-68, Cu-64, Zr-89, In-111) and/or therapeutic radioisotopes (Lu-177, Ac-225, Tb-161, Cu-67, Pb-212) is considered an asset.
  • Experienced in quality control testing of radiopharmaceuticals. Hands-on experience with radio-HPLC, radio-ITLC and GC are considered assets.
  • Knowledge of environmental health and radioprotection requirements are considered assets.
Physical Demands/Travel:
  • Position will require up to 10% of travel within North America. A valid passport and eligible to travel into these countries are required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.Work Environment:
  • Position requires to be onsite during the work week.
  • This role works in a hospital setting and it is mandatory for all employees to complete health screens before onboarding. In the event the screen results show non-immunity, vaccines may need to be administered.
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.Eli Lilly Canada is committed to employment equity. We encourage applications from qualified women, members of visible minorities, aboriginal peoples, and persons with disabilities.Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively \xe2\x80\x9cLilly\xe2\x80\x9d) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively \xe2\x80\x9cLilly\xe2\x80\x9d) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.#WeAreLilly

Eli Lilly

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Job Detail

  • Job Id
    JD2289593
  • Industry
    Not mentioned
  • Total Positions
    1
  • Job Type:
    Full Time
  • Salary:
    Not mentioned
  • Employment Status
    Permanent
  • Job Location
    Toronto, ON, Canada
  • Education
    Not mentioned