Senior Research Associate, Antibody Discovery & Engineering

Vancouver, BC, Canada

Job Description


Company Description
Zymeworks is a publicly listed (NASDAQ:ZYME) clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation, biospecific and multifunctional biotherapeutics, initially focused on the treatment of cancer. Zymeworks\' suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly-differentiated product candidates.

Why Work With Us

Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful - we care about each other as well as the patients we serve. We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.

Zymeworks is proudly headquartered in our brand new, net-zero facility located in the vibrant Main St biotech hub of Vancouver, BC, with operations in Seattle, WA and Dublin, Ireland. We offer a hybrid work environment with most team members working in-office three days per week.

Key Responsibilities

  • Executes experiments as per project objectives, with an emphasis on cell line engineering, including vector design, to support in vitro characterization of antibody drug conjugates
  • Performs various cloning protocols and integrates new techniques to enable high throughput processing
  • Executes high throughput PCR-based assays
  • Executes in vitro assays to characterize monoclonal antibodies
  • Generates high quality, reproducible data to assist in the selection of lead therapeutic molecules and for elucidation/validation of targets for therapeutic development.
  • Analyzes, interprets and presents data.
  • Keeps up with ongoing projects through attention to internally generated data.
  • May assist in preparation of patent applications, research reports and/or scientific papers.
  • Assists in maintaining a clean, organized and operational lab.
  • Conducts all activities in accordance with scientific standards, OH&S regulations and established policies and practices.
  • Adheres to standard procedures for generating, documenting and archiving data. An accurate, up to date lab notebook or electronic notebook is mandatory.
  • Fosters effective and collaborative working relationships with fellow employees and management.
Education and Experience
  • MSc (in Molecular Biology preferred) with 2-3 years\' related experience or an equivalent combination of education and experience.
Skills and Abilities:
  • Experience in generating engineered stable cell lines using transfections, CRISPR/Cas9 tools or lentiviral systems. Experience in vector design is desirable.
  • Proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional team. Ability to establish and maintain effective working relationships.
  • Good organizational skills and the ability to work effectively in a high paced, fast changing environment while balancing multiple activities. Results-oriented individual.
  • Ability to contribute to the development of new methodologies to address scientific questions.
  • Critical observation skills and good statistical analysis capability.
  • Good oral, presentation, and scientific/technical writing skills.
  • MS Office proficiency.
  • Strong knowledge and experience in performing lab techniques and methods which may include, but not limited to
  • cell-based techniques such as tissue culture, cell transfections, flow cytometry and FACS
  • molecular biology techniques, such as plasmid design, PCR, transformations, advanced cloning, gene editing
  • sequence analysis, including NGS-based antibody analysis
Total Rewards

We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies.

Our team enjoys:
  • Industry leading vacation and paid time off
  • Excellent health and wellness benefits
  • Zymelife health and wellness benefits
  • Paid time off to volunteer in your community
  • Matching RRSP / 401K program
  • Employee Share Purchase Program
  • Employee Equity Program
All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability.

NOTE TO AGENCIES: Zymeworks values our relationships with our recruiting partners. We only accept resumes from those partners who have been contracted with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract.

Date: Apr 6, 2023

Zymeworks

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Job Detail

  • Job Id
    JD2168948
  • Industry
    Not mentioned
  • Total Positions
    1
  • Job Type:
    Full Time
  • Salary:
    Not mentioned
  • Employment Status
    Permanent
  • Job Location
    Vancouver, BC, Canada
  • Education
    Not mentioned