Job Description

Company Description
UHN is Canada's #1 hospital and the world's #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.
UHN's vision is to build A Healthier World and it's only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

Union: Non-Union
Number of vacancies: 1
Site: Krembil Brain Institute
Department: Research
Reports to: Research Institute Director
Hours: 37.5 hours per week
Shifts: Day
Status: Permanent Full-time
Closing Date: November 30, 2025
Position Summary
The Krembil Brain Institute (KBI) at University Health Network (UHN), a University of Toronto (U of T) teaching hospital, is seeking applicants for the Piyush Kumar and Usha Agarwal Chair in Neurodegenerative Disease Research. The successful candidate currently holds at minimum a Senior Scientist appointment at the Krembil Brain Institute and must already hold, at minimum, Associate Professor faculty status at the University of Toronto within the Temerty Faculty of Medicine. The term of the Chair position is 5 years.
The Piyush Kumar and Usha Agarwal Chair in Neurodegenerative Disease Research will develop and lead research to explore the fundamental mechanisms of protein misfolding in neurodegeneration and to lead efforts to develop novel therapies. The Chairholder will explore the mechanisms by which proteins, especially Tau and a-synuclein, misfold and aggregate in the brain, as well as how these proteins interact. They will also identify molecular processes that could be targeted using immunotherapy or gene therapy against misfolded or pathogenic proteins to prevent or halt neurodegeneration.
The Chairholder will be encouraged to conduct transdisciplinary research, drawing insights from multiple fields, such as molecular biology, genetics, biochemistry, neuroimmunology and systems neuroscience, and to champion neurodegeneration research in Canada and beyond.
Salary will be commensurate with qualifications and experience.
A complete package MUST include the following elements. Please combine these into a SINGLE file to attach to the application:

• Cover letter
• Curriculum vitae
• Research program proposal (up to 2 pages, excluding references)
• Teaching and mentorship statement (1/2 page)
• Equity, diversity and inclusion statement (1/2 page)

Duties

• The successful applicant has established and will continue to maintain an original, competitive, and independently funded research program of international caliber
• Will be expected to teach at the undergraduate and graduate levels

Qualifications

• Candidates must have a Ph.D. and/or M.D. in a relevant scientific discipline, as well as significant postdoctoral research experience and an established record of research excellence
• The successful applicant is appointed as a Senior Scientist at the Krembil Brain Institute at UHN
• Candidates are expected to demonstrate evidence of 1) outstanding peer-reviewed publications in leading journals; 2) successful research funding (peer-reviewed grants, fellowships, etc.); 3) presentations at significant conferences; and 4) significant leadership experience in directing a research team

Additional Information
Why join UHN?
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP

) * Close access to Transit and UHN shuttle service

• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.
All applications must be submitted before the posting close date.
UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.
Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.
UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.
We thank all applicants for their interest, however, only those selected for further consideration will be contacted.

Skills Required