Job Description

Company Description
UHN is Canada's #1 hospital and the world's #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.
UHN's vision is to build A Healthier World and it's only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

Union: Non-Union
Number of Vacancies: 1
Site: Princess Margaret Cancer Centre
Department: Research
Reports to: Research Institute Director
Hours: 37.5 Per Week
Shifts: Monday - Friday
Status: Permanent Full-Time
Closing Date: November 14, 2025
Position Summary
Principal Investigator (early career) in Cancer Biology
The Princess Margaret Cancer Centre (PM) at the University Health Network (UHN), a cancer research institute affiliated with the University of Toronto, seeks an early-career faculty Scientist (full time Assistant Professor level) to establish an independent world-class research program in Cancer Biology. Successful candidate will be supported by a generous start-up package, independent modern laboratory space, full salary and assistance in obtaining cross-appointment to the University of Toronto. PM appointment is expected at the rank of Scientist, on a career path to Senior Scientist over a six-year period (tenure-track-equivalent).
Successful candidates will develop an independent research program with extramural funding. Applications across the spectrum of cancer biology are encouraged, with emphasis on functional and mechanistic research towards development of future therapies. Examples include but are not limited to aging, inflammation, cellular stress, functional genomics, structural biology, and chemical biology. Use of novel research platforms and technologies will be prioritized, complementing institutional expertise and resources in genomics, proteomics, computational and structural biology, immunology and high-throughput biology, supported by cutting-edge research core facilities.
The Princess Margaret Cancer Centre is one of the largest comprehensive cancer research and treatment facilities in the world, located in the heart of the vibrant and diverse city of Toronto, Canada. Through its commitment to innovation, research and education, the Princess Margaret Cancer Centre perennially ranks in the top 10 cancer research centers in the world and is home to over 350 faculty clinicians and scientists, including over 65 principal investigators appointed at the research institute. Standing at the frontier of medical and experimental oncology, the Princess Margaret Cancer Centre is world-renowned for groundbreaking cancer discoveries in stem cells, genetics and epigenetics, immuno-oncology, protein structural biology and proteomics.
Qualifications

• PhD and/or MD or equivalent designation
• Extensive experience in one or more functional and cancer biology fields of research
• An exceptional track record evidenced by high impact discoveries (publications and/or intellectual properties & patents), dissemination of research at formal scientific meetings, and participation in the education and supervision of students and trainees
• Strong leadership skills
• Effective communication (written and verbal), problem-solving and consensus building skills
• Excellent organizational, interpersonal and time management skills.

Application: A complete package MUST include:

• cover letter,
• full academic curriculum vitae (CV),
• 3-page statement of proposed research objectives, highlighting the major themes of research to be completed over the next five years, and long-term goals.

Please combine all documents into a SINGLE file and send to the Research Directorate Office, Princess Margaret Cancer Centre,
, by November 14, 2025.
A faculty Search Committee will shortlist applications based on the applicant's scientific excellence, alignment with Princess Margaret Cancer Centre research programs. Candidates invited for in-person interviews will be asked to arrange submission of reference letters.
Additional Information
Why join UHN?
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP

) * A generous parental leave program including full salary support during leave

• Close access to Transit
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.
All applications must be submitted before the posting close date.
UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.
Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.
UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.
We thank all applicants for their interest, however, only those selected for further consideration will be contacted.

Skills Required