This position is a part of the Association of the Academic Staff of the University of Alberta (AASUA). In accordance with the Trust/Research Academic Staff Agreement, this position offers a comprehensive benefits package found on our Benefits Overview page and annual salary range of $58 210 - $65 490.This position has an approximate appointment of 12 months. Location Work primarily takes place in-person at North Campus Edmonton. Working for the University of Alberta The University of Alberta acknowledges that we are located on Treaty 6 territory, and respects the histories, languages and cultures of First Nations, M\xc3\xa9tis, Inuit and all First Peoples of Canada, whose presence continues to enrich our vibrant community. The University of Alberta is teeming with change makers, community builders, and world shapers who lead with purpose each and every day. We are home to more than 40,000 students in 200+ undergraduate and 500+ graduate programs, over 13,000 faculty and staff, 260,000 alumni worldwide and have been recognized as one of Canada\xe2\x80\x99s Greenest Employers for over a decade. Your work will have a meaningful influence on a fascinating cross section of people\xe2\x80\x94from our students and stakeholders, to our renowned researchers and innovators who are quite literally curing diseases, making discoveries and generating solutions that make the world healthier, safer, stronger, and more just. Working for the Department/Faculty The Department of Oncology consists of the School of Radiation Therapy and the following 7 Divisions: Experimental Oncology, Medical Oncology, Medical Physics, Oncologic Imaging, Palliative Care Medicine, Radiation Oncology, and Surgical Oncology. Within the Cross Cancer Institute, several of these academic divisions also comprise hospital departments. The Division of Oncologic Imaging is unique to the University of Alberta. Our Department, the fourth largest in the Faculty of Medicine & Dentistry and located at three sites on the University of Alberta campus. Position The RA will be responsible to Dr. Ronald B. Moore and his research collaborators (including other laboratory personnel) for carrying out the experiments detailed in New Frontiers in Research Fund-Exploration (NFRFE) in a good laboratory practice (GLP) fashion. This is a translational biomedical cancer research project on radioPDT, photodynamic therapy, radiotherapy, nanoparticle, theranostic, contrast agent, hypoxia, prostate cancer, drug delivery. Duties
The RA will keep meticulous electronic records of each experiment.
Maintenance of animal ethics and standard lab operating procedures (SOPs).
Maintenance of precious engineered cell lines.
Radiation safety knowledge needs to be strictly followed.
Experimental animals models need to be maintained and cared for with vivarium staff.
Advanced imaging on core facility equipment needs to be scheduled and conducted with staff.
Nanoparticle formulation, quality assessment, maintenance, and shipping
Fluorescent imaging and photochemistry
Immunobiology
Tumor biology
Cell signaling
Animal survival assays
Cell survival assays
Drafting and assistance publishing
Qualifications
PhD in Medicine, Cancer Sciences, Molecular Biology, or related discipline
5 years of experience in tumor studies using different xenograft mice models
10 years of experience in mammalian cell culture, molecular biology, tumor biology and vascular biology related research
Experience in in vitro and ex vivo 3D angiogenesis
Working knowledge and experience in nanotechnology, photodynamic therapy and radiation oncology
Experience in writing application for ethics approval to use animals for research
Strong publication records in peer-reviewed journals
Experience in the synthesis and characterizations of nanoparticles (NPs), and encapsulation of NPs and photosensitizers into nanocarriers
Experience in isolation of primary endothelial cells from human umbilical cords and endothelial progenitor cells from blood
Extensive knowledge in mammalian cell culture, in vitro assays, cell toxicity, proliferation and invasion assays
Extensive knowledge in molecular techniques such as immunohistochemistry (IHC), immunoprecipitation (IP), DNA/RNA extraction, real time PCR (qPCR), and Western blotting etc.
Experience in the use of confocal and transmission electron microscopy
Experience in single cell sequencing
How to Apply Kindly submit:
Cover Letter
Curriculum Vitae
References
How to ApplyNote: Online applications are accepted until midnight Mountain Standard Time of the closing date. All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority. If suitable Canadian citizens or permanent residents cannot be found, other individuals will be considered. The University of Alberta is committed to an equitable, diverse, and inclusive workforce. We welcome applications from all qualified persons. We encourage women; First Nations, M\xc3\xa9tis and Inuit persons; members of visible minority groups; persons with disabilities; persons of any sexual orientation or gender identity and expression; and all those who may contribute to the further diversification of ideas and the University to apply.
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