Job Description

Altasciences is a forward-thinking, mid-size contract research organization offering pharmaceutical and biotechnology companies a proven, flexible approach to preclinical and clinical pharmacology studies, including formulation, manufacturing and analytical services. For over 25 years, Altasciences has been partnering with sponsors to help support educated, faster, and more complete early drug development decisions. Altasciences' integrated, full-service solutions include preclinical safety testing, clinical pharmacology and proof of concept, bioanalysis, program management, medical writing, biostatistics, and data management, all customizable to specific sponsor requirements. Altasciences helps sponsors get better drugs to the people who need them, faster.
The Principal Scientist, LBA will supervise a team of scientists in the Ligand binding assay department to ensure the scientific and regulatory excellence, client service, performance, productivity and efficiency of the group's operations and logistics. The Principal Scientist is an the expert in the field of Oligonucleotides Bioanalysis by hybridization ELISA. He or she stays appraised of the status of all projects and recommends resource adjustment based on deliverable schedules. Provides scientific and operational guidance within their area of expertise and promote efficiency initiatives that have impact on improving productivity and profitability. He or she may be assigned to projects based on scientific competency and training.
Main Responsibilities:

• Responsible for personnel management activities of assigned staff such as: scheduling, personnel actions, training and development, providing regular direction and feedback on performance, disciplinary actions and preparing and delivering annual performance and salary reviews;
• Manage direct reports to ensure project timelines are respected and communicates any delays in a prompt fashion;
• Provide Scientific support to assigned Bioanalytical Principle Investigator in the area of Hybridization ELISA for ASO quantitation in various matrices to support both nonclinical and clinical studies;
• Responsible for set up and implementation of training for technical and scientific LBA staff;
• Responsible for improved efficiency initiatives in the laboratory, including scheduling assays, operations and improving workflows;
• Review costing assessments and scheduling projects with business development and operation coordinator;
• Review forecast and identifying critical projects to maximize for revenue recognition;
• Support Senior Director as needed with client interactions, scientific troubleshooting and support of scientific staff;
• Contributes to the growth and development of Altasciences ligand binding assay services, as well as participate in strategic planning;

Responsible for working closely with other MD management members and serve as back-up when any of them is out of office;

• Can be assigned as Bioanalytical Principal Investigator and will manage and conduct hybridization ELISA method development, qualification, validation and production studies for clinical and non-clinical studies in compliance with the protocol/study plan, amendments, GCP, GLPs, SOPs and Best Practices;
• Respecting Health and Safety standards in terms of personal protection, laboratory maintenance, and work procedures;
• Other related tasks.

Desired Profile:

• Master's or Bachelor's degree in Biochemistry, Immunology or relevant field;
• Preferred experience in regulated clinical and/or preclinical studies within the area of expertise (immunogenicity, PK or Biomarker, Oligonucleotide) with 5-10 years of experience in CRO or pharmaceutical company or equivalent;
• Good organizational skills;
• Highly flexible and sense of urgency;
• Excellent troubleshooting skills and attentive to details;
• Client oriented and ability to coach/mentor people;
• Be able to easily read and understand study plans and protocols,
• Good communication both written and verbal in French & English.;
• Must understand general SOPs and have an excellent knowledge of GCP/GLP regulations.

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Altasciences is an equal opportunity employer committed to diversity and inclusion. Our goal is to attract, develop and retain highly talented employees from diverse backgrounds, allowing us to benefit from a wide variety of experiences and perspectives. All qualified applicants will receive consideration for employment without regard to age, race, color, religion, creed, sex, sexual orientation, gender identity, national origin, disability or any other protected grounds under applicable legislation. Reasonable accommodations for persons with disabilities during the recruitment process are available upon request. Join us at Altasciences!