Job Description

Company DescriptionThe University Health Network, where \xe2\x80\x9cabove all else the needs of patients come first\xe2\x80\x9d, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of \xe2\x80\x9cTransforming lives and communities through excellence in care, discovery and learning\xe2\x80\x9d, the University Health Network (UHN), Canada\'s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.Union: Non-Union
Site: Toronto Medical Discovery Tower
Department: The Winer Lab
Reports to: Principal Investigator
Work Model: On-Site
Grade: V0:90
Hours: 37.5 hours per week
Salary: $51,750 Annually minimum.
Shifts: Monday to Friday
Status: Temporary Full-Time
Closing Date: July 13, 2024Position SummaryThe Winer lab at UHN studies how the immune system influences chronic inflammation during insulin resistance and/or aging (see sample lab papers: Tsai et al Cell Metab 2018, 922-34; Ghazarian et al Science Immunol 2017, Apr 21; Winer et al Cell Metab 2016, 413-26; Luck et al Cell Metab 2015, 527-42; Winer et al Nature Med 2011, 610-7; Winer et al Nature Med 2009; 921-9). We also have an interest in mechanoimmunology (Wu et al Nat Commun 2024; Du et al Nat Rev Immunol 2023; Charkraborty et al Cell Rep 2021). We use immunology, molecular biology, including multi-omic assays, mouse models, and tissue culture assays to elucidate mechanisms by which immune cells and immune molecules influence inflammation in tissues.We are looking for an independent and highly motivated recent PhD, MD or MD/PhD graduate with a strong background in immunology to study mechanisms of inflammation with age or in chronic diseases of age, including diabetes, using mouse and cell culture models.DutiesThe selected applicant will have the opportunity to contribute to several projects, including: * The immune system in obesity and insulin resistance

• The immune system in aging
• The impact of mechanical forces on immune and other cells

The successful candidate will also receive training and mentorship in key developmental areas. These areas include grant writing, manuscript review, supervision of trainees, conference travel and networking opportunities.Qualifications

• Highly motivated recent PhD, MD or MD/PhD graduate.
• Expertise in Immunology is required.
• Applicants should be ambitious, independent and hard-working.
• Post doc will be given a high impact project but will also have creative freedom to pursue their own ideas.
• Expertise with animal models and genetically modified mice is required.
• Expertise in flow cytometry, cell sorting, immunological assays, immune cell or organoid culture work, Western blotting, and ELISA is highly recommended.
• Previous work in bioinformatics of RNA sequencing datasets is also especially desirable.
• Publications in high quality journals required (minimum of 3 publications, at least 1 first author).
• Excellent verbal and written communication skills.

Additional InformationWhy join UHN?In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP

) * Close access to Transit and UHN shuttle service

• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN\'s attendance management program, to be eligible for consideration.All applications must be submitted before the posting close date.UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.We thank all applicants for their interest, however, only those selected for further consideration will be contacted.

University Health Network