Job Description

Regular/Temporary

Temporary

Job Title

POST DOCTORATE FELLOW

Job ID

69480

Location

HSC- Central Campus

Open Date

06/23/2025

Job Type

Limited Term (=12 month)

Close Date

07/22/2025

Employee Group

Pos Doc (Union&NonUnion)

Favorite Job

Department

Biochemistry

Contract Duration

12.1 Months

Hours per Week

35

Posting Details

Schedule

9:00am to 5:00pm, Monday to Friday On Site Requirement

Education Level/Career Level

PhD in the field of cancer biology/bioinformatics/immunology, systems biology, functional genomics, cell and molecular biology, biochemistry, computational biology or related field with two years (min) of relevant experience

Dr. Hong Han's Lab is part of Biochemistry and Biomedical Sciences (BBS) and the Centre for Discovery in Cancer Research (CDCR) at McMaster University. Dr. Han is a Canada Research Chair, Tier 2 in Cancer System Biology, and our team strives to create a collaborative, supportive, and stimulating environment for multi-disciplinary research. The Han Lab works at the interface of cancer biology, RNA and multilayer gene regulation, and high-throughput technologies. We have pioneered the development and application of several integrated technological platforms for large-scale genetic/drug screening and ultra-high-throughput single-cell profiling. Leveraging the power of these systematic experimental and bioinformatic approaches, together with in vitro, in vivo, and patient cohort studies, we discover multilayer regulatory mechanisms underlying cancer progression and RNA-multimodal therapeutics for treatment-resistant cancer.


We are recruiting for a motivated

postdoc,

who will, in consultation with the Principal Investigator, lab researchers, and collaborators, design and apply innovative experimental and computational methodologies as well as in vitro and in vivo models to drive high-throughput discovery of cancer mechanisms and therapeutics, especially for treatment-resistant cancers. Collaborating with biologists and clinicians in related fields, they will lead the generation and analysis of multi-omics experiment data, including single-cell multi-omics characterization, spatial transcriptomics/proteomics profiling, and functional genomics, in the context of both basic and translational cancer research.

Requirements:

PhD in the field of cancer biology/bioinformatics/immunology, systems biology, functional genomics, cell and molecular biology, biochemistry, computational biology or related field with two years (min) of relevant experience A high degree of independence and motivation, along with a willingness to work in a team, given the project's cooperative nature Strong communication (oral and written), collaboration, project management, and mentoring skills Strong background and skills in single-cell multi-omics, bioinformatics, functional genomics, advanced cancer models, and/or programming robotic equipment Proven track record of peer-reviewed publications

Additional assets (but not required)

Demonstrated ability to learn new high-throughput techniques and train others is desired Excellent milestone and time management skills Experience with the integration of multi-omics data and clinical information is considered an asset Background in RNA omics and alternative splicing is considered an asset Familiarity with programming languages, high-performance computing environments, and machine and statistical learning is considered an asset

This position will be held at McMaster University, recognized as one of Canada's most research-intensive universities. In our teaching, research, and scholarship, we are committed to creativity, innovation, and excellence. We value integrity, quality, inclusiveness, and teamwork in everything we do. We inspire critical thinking, personal growth, and a passion for lifelong learning. We serve the social, cultural, and economic needs of our community and our society. Hamilton is 45 minutes from Toronto. It is also about an hour from Buffalo, New York, and less than an hour from Niagara Falls. McMaster University is located on the traditional territories of the Haudenosaunee and Mississauga Nations and within the lands protected by the "Dish With One Spoon" wampum agreement.


This postdoc fellowship provides a unique interdisciplinary opportunity to develop and leverage integrated, state-of-the-art multi-omics approaches and cancer models to systematically discover cancer mechanisms, biomarkers, and therapeutic targets of hard-to-treat cancers, leading to future personalized medicine.

How To Apply

Qualified applicants are invited to submit their CV, a cover letter/statement of interest, and a list of 3 reference contact information via online.

Employment Equity Statement

McMaster University is located on the traditional territories of the Haudenosaunee and Mississauga Nations and within the lands protected by the "Dish With One Spoon" wampum agreement.


The diversity of our workforce is at the core of our innovation and creativity and strengthens our research and teaching excellence. In keeping with its Statement on Building an Inclusive Community with a Shared Purpose, McMaster University strives to embody the values of respect, collaboration and diversity, and has a strong commitment to employment equity.


The University seeks qualified candidates who share our commitment to equity and inclusion, who will contribute to the diversification of ideas and perspectives, and especially welcomes applications from indigenous (First Nations, Metis or Inuit) peoples, members of racialized communities, persons with disabilities, women, and persons who identify as 2SLGBTQ+.


As part of McMaster's commitment, all applicants are invited to complete a confidential Applicant Diversity Survey through the online application submission process. The Survey questionnaire requests voluntary self-identification in relation to equity-seeking groups that have historically faced and continue to face barriers in employment. Please refer to the Applicant Diversity Survey - Statement of Collection for additional information.


Job applicants requiring accommodation to participate in the hiring process should contact:

Human Resources Service Centre at 905-525-9140 ext. 222-HR (22247), or Faculty of Health Sciences HR Office at ext. 22207, or School of Graduate Studies at ext. 23679

to communicate accommodation needs.

Vaccination Mandate - FHS

This position is located in a host hospital or other healthcare site that has an active vaccination mandate in place. Successful applicants will need to comply with these and any other health and safety measures necessary as part of their appointment.

Interview Experience

At McMaster University, we believe in a comprehensive and inclusive interview process. Our interview methods encompass a variety of approaches that allow our hiring teams to provide a flexible and accessible experience for engaging with our candidates. Throughout your recruitment process at McMaster, you may be requested to participate in a variety of formats, that may include in-person, virtual or recorded interviews. If you have any questions as you move through the hiring process, please reach out to talent@mcmaster.ca or the HR contact associated with your position of interest.