Job Description

Position: Bioinformatician II
Location: MaRS Centre, Toronto
Department: Genome Informatics
Reports To: Director, Genome Informatics and Principal Investigator I
Salary: Commensurate with level of experience
Hours: 35 hours/week
Job Type: Hybrid
Status: Full-time, Temporary (Maternity Leave coverage until November 2024)

The Ontario Institute for Cancer Research (OICR) is seeking a talented Bioinformatician II to join its Data Curation and Bioinformatics team under the Data Coordination Centre (DCC) of the International Cancer Genome Consortium (ICGC) Accelerating Research in Genomic Oncology (ARGO) ( ). As a successful candidate, you will help to meet ARGO\xe2\x80\x99s ambitious goal of uniformly analyzing the genomes of more than 100,000 participants and linking these data to high-quality clinical information. This data will be used by cancer researchers around the world to develop new diagnostics and therapeutics for cancer.

We are looking for a talented individual with a passion for bioinformatics in computational cancer genomics and who wants to become part of a world-class team building cutting-edge solutions from the ground up. This position would be a great opportunity for a recent graduate to join an established diverse team. If this sounds like you, please get in touch!

This position is temporary, full-time to cover a maternity leave until November 2024.

To learn more about working at OICR, visit our .

The responsibilities include:

• Provide technical support to ICGC ARGO program members for resolving data submission issues and to ensure smooth data processing.
• Provide Helpdesk support for external users in an efficient and timely manner on data inquiries such as data accessibility, data download and portal functionality.
• Assist in developing and maintaining analysis pipelines and computational workflows to perform uniform analyses.
• Perform routine workflow execution, monitoring and debugging for ICGC-ARGO processing center in the Regional Data Processing Centre.
• Assist in implementation of tools for data quality control, validation and reporting.
• Perform benchmarking tests to evaluate different solutions and suggest optimizations.
• Support business analysts to assist the translation of bioinformatics needs into software functional requirements and specifications.
• Evaluates implemented solutions and tools against requirements and use cases.
• Contribute to preparing and maintaining documentation of standard operating procedures and user guides.
• Other assigned scripting and data handling tasks.

Qualifications:

• Undergraduate degree or higher in bioinformatics, genomics, computational biology, or computer sciences, or equivalent education or work experience.
• Good understanding of molecular biology concepts and genetics.
• Extensive programming experience with Python, preferably in large-scale projects.
• Experience with bioinformatics resources, databases, tools and common standard formats.
• Working experience in analyzing large genomics datasets (raw sequencing data, gene expression, germline and somatic mutational events, copy number variants, methylation, etc.).
• Expertise with good software development practices, including using version control and build/test automation and issue tracking system (ie. git, JIRA).
• Experience using existing scientific workflow systems, such as CWL/WDL/Nextflow is an asset
• Experience with container software (docker, singularity)
• Common bioinformatic tools like samtools, GATK, etc \xe2\x80\xa6
• Demonstrated ability to work both independently and in a collaborative team environment and meet required timelines.
• Be highly detail-oriented and possess excellent verbal and written communication skills.
• Communicates effectively with multiple stakeholders including researchers and staff in a diverse team environment.

OICR is a collaborative, not-for-profit research institute accelerating the development of new cancer research discoveries for patients around the world while maximizing the economic benefit of this research for the people of Ontario. We are dedicated professionals who bring expertise to each of our roles. We are looking for individuals who share our values of excellence, innovation, collaboration, impact, responsibility and community.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Colleges and Universities.

For more information about OICR, please visit the website at .

CLOSING DATE: Until Filled

OICR is committed to fostering a climate of equity, diversity, inclusion, and accessibility. This commitment is central to, and mutually supportive of, our research excellence mandate. We welcome and respect the diversity of all members of our community and we support an inclusive culture for all. We welcome all applicants, and encourage applications from racialized persons, Indigenous Peoples, women, persons with disabilities, LGBTQ2S persons, and others who may contribute to furthering a diversity of ideas within our community. OICR is committed to fair assessment of a candidate\xe2\x80\x99s abilities, and consideration for diversity of thought, method, and experience. Providing an accessible workplace and recruitment process is important to us, as described in our Accessibility Plan ( ). Should you require accommodation during any stage in the recruitment process, please complete the form at the bottom of page . Information received related to accommodation will be handled confidentially.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted.

Resume Format: If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application. Please attach your resume as a .pdf or .doc file.

Ontario Institute for Cancer Research