Job Description

For Current Gilead Employees and Contractors:

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At Gilead we believe every employee deserves a great leader. As a people leader now or in the future, we expect that you will model and create an environment of inclusion, be intentionally focused on the hiring, development, growth and retention of talent, and empower teams to align and achieve goals.



Sr. Research Scientist II, Process Development - Edmonton, Alberta

Gilead Sciences in Edmonton, Alberta, Canada, currently has an excellent opportunity for a highly motivated scientist to join our Process Development group in the Pharmaceutical Development & Manufacturing (PDM) organization. With your commitment and drive, you will be part of a cross-functional drug development team whose goal is to develop curative medicines helping millions of people live healthier, more fulfilling lives. With state-of-the-art research facilities and a team of experienced scientists who are passionate about developing drugs, the Process Development group at Gilead empowers every chemist to take part in the act of innovation. You will see the tangible results of your contributions in this dynamic workplace, where every individual matters, and everyone has a chance to enhance their skills through on-going development. Our science focused pursuit of excellence and teamwork has resulted in breakthrough development of many life-changing novel marketed products that are benefiting millions of people. With a robust pipeline of drug candidates at every developmental stage at Gilead, you will have ample opportunities to make meaningful contribution to our mission to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases. Gilead\xe2\x80\x99s core values of integrity, inclusion, teamwork, excellence, and accountability shape our culture and are the foundation of our future success. Challenge yourself and make a difference in the world \xe2\x80\x93 Make your mark here at Gilead.

Job Responsibilities:

Leads or contributes to a Process Chemistry team responsible for developing chemical processes for the manufacturing of drug substances, from route selection to active pharmaceutical ingredient (API) delivery

Leads or participates in the planning and execution of experimentation while considering process efficiency, scalability, safety, regulatory aspects, and cost of goods.

Proposes alternative chemistry, including new route selection and step optimization

Demonstrates technical knowledge, scientific creativity, and collaboration skills in the development and execution of research for the preparation of novel chemical substances

Provides direction or mentorship to members of project teams in the initiation and execution of laboratory experimentation

Provides technical support for manufacturing processes performed under cGMP in laboratory manufacturing and large-scale manufacturing operations

In collaboration with senior scientists, develops project strategy for manufacturing of drug substances to support clinical studies and commercialization

Prepares and reviews technical documents including research reports, process development reports, and documentation for the manufacturing of chemical substances e.g. Master Batch Records (MBRs)

Collaborates across functional areas including analytical chemistry, quality assurance, and manufacturing to accomplish project goals. Acts as a subject matter expert for cross-functional teams and research personnel

Ensures that all experimentation is carried out in accordance with appropriate standard operating procedures (SOPs), maintaining quality, safety, and environmental standards

Knowledge, Experience and Skills:

PhD in Chemistry with 7+ years of experience; Or BS or MS degree with extensive industry experience

Experience in planning and executing multi-step synthesis of organic molecules

Familiarity with purification and analytical techniques, including HPLC, LCMS and NMR

Experience scaling up synthetic routes and developing safe processes

Experience with kilo lab, pilot plant and/or plant operations

Familiarity with cGMP regulatory guidelines

Experience with project and people management

Strong desire to work in multi-disciplinary teams, learn new skills and proactively solve problems

Excellent verbal and written communication skills and strong interpersonal collaboration skills

Strong organizational and planning skills

Gilead is an equal opportunity employer.

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

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