Job Description

Job Title: Senior Statistical Programmer (Remote Canada)
Location: Remote (Canada-based)
Employment Type: Contract to Hire
About the Role:
We are seeking an experienced and detail-oriented Senior Statistical Programmer to join our growing team. This is a remote position open to candidates residing in Canada. The ideal candidate will bring robust hands-on expertise in statistical programming with a focus on end-to-end clinical trial data processes including SDTM, ADaM, TLFs, and associated documentation. Strong oncology domain knowledge and hands-on experience with ADTTE and oncology TLFs is essential for success in this role.
Key Responsibilities:

• Develop, validate, and maintain SDTM and ADaM datasets in compliance with CDISC standards.
• Program and validate Tables, Listings, and Figures (TLFs) for clinical trial submissions and reports.
• Prepare and review study-level documentation including SDRG, ADRG, Define.xml, and Pinnacle 21 reports.
• Ensure programming deliverables meet quality standards and regulatory compliance requirements.
• Work cross-functionally with statisticians, data managers, and medical writers to support clinical study objectives.
• Provide programming support for oncology trials, with a focus on ADTTE derivations and efficacy/safety TLFs.
• Mentor junior programmers and contribute to process improvements and best practices.

• Bachelor's or Master's degree in Computer Science, Statistics, Mathematics, Life Sciences, or a related field.
• Minimum 5 years of experience in statistical programming within the pharmaceutical or CRO industry.
• Strong knowledge and hands-on experience with CDISC standards (SDTM, ADaM).
• Proven experience with oncology studies, particularly ADTTE and oncology-specific TLFs.
• Proficiency in SAS programming (Base, Macro, SQL, and/or Graph).
• Familiarity with regulatory submission standards and tools (e.g., Pinnacle 21, Define.xml creation).
• Ability to work independently in a remote environment and manage multiple priorities effectively.
• Excellent communication and documentation skills.