Job Description

Dot\xc3\xa9s d\xe2\x80\x99une expertise in\xc3\xa9gal\xc3\xa9e en immunologie et pr\xc3\xa9sents en Am\xc3\xa9rique du Nord (c\xc3\xb4te Est et Ouest) et en Europe, Nexelis est l\xe2\x80\x99un des principaux prestataires de services dans le domaine du d\xc3\xa9veloppement et l\xe2\x80\x99analyse de tests biologiques sp\xc3\xa9cialis\xc3\xa9s en infectiologie, m\xc3\xa9tabolisme, et canc\xc3\xa9rologie. Notre \xc3\xa9quipe polyvalente de scientifiques, munie de plateformes technologiques \xc3\xa0 la fine pointe du progr\xc3\xa8s a jou\xc3\xa9 un r\xc3\xb4le essentiel dans le d\xc3\xa9veloppement, la qualification, validation de tests et leur utilisation en haut d\xc3\xa9bit dans plus de 100 dossiers associ\xc3\xa9s \xc3\xa0 l\xe2\x80\x99approbation par la FDA de nouvelles entit\xc3\xa9s mol\xc3\xa9culaires, comprenant des vaccins majeurs, des antiviraux et des produits d\xe2\x80\x99immunoth\xc3\xa9rapie, de th\xc3\xa9rapie g\xc3\xa9nique ou cellulaire.

Nexelis, une entreprise de Q2 Solutions, continue sa croissance et nous sommes pr\xc3\xa9sentement \xc3\xa0 la recherche d\xe2\x80\x99un (e) candidat(e) motiv\xc3\xa9(e) pour occuper le poste de scientifique, d\xc3\xa9veloppement de tests pour notre \xc3\xa9quipe de Bacteriology.

Vos principales responsabilit\xc3\xa9s :

• Connaissances en diff\xc3\xa9rents types d\xe2\x80\x99essais qui vont de la pr\xc3\xa9paration des \xc3\xa9chantillons, les tests au labo \xc3\xa0 l\xe2\x80\x99analyse de donn\xc3\xa9es.
• Planifier et ex\xc3\xa9cuter les exp\xc3\xa9riences de laboratoire en suivant les instructions (PON)
• Participer au d\xc3\xa9veloppement des essais selon les requis des clients, incluant les phases de qualification et validation
• Consigner les r\xc3\xa9sultats dans des cahiers de laboratoire selon les SOPs \xc3\xa9tablies ;
• Faire le suivi et maintenir l\xe2\x80\x99inventaire des r\xc3\xa9actifs et mat\xc3\xa9riels ;
• Suivre les proc\xc3\xa9dures en place afin de maintenir la qualit\xc3\xa9 et l\xe2\x80\x99int\xc3\xa9grit\xc3\xa9 des r\xc3\xa9sultats
• Analyser les r\xc3\xa9sultats obtenus et les synth\xc3\xa9tiser au besoin
• Effectuer l\xe2\x80\x99entretien et la calibration des instruments lorsque n\xc3\xa9cessaire
• Participer proactivement \xc3\xa0 toutes initiatives permettant l\xe2\x80\x99optimisation des op\xc3\xa9rations, la satisfaction de nos clients et la croissance de l\xe2\x80\x99entreprise

Ce que nous recherchons :

• Exp\xc3\xa9rience pertinente dans le d\xc3\xa9veloppement, la qualification, la validation et la r\xc3\xa9solution de probl\xc3\xa8mes, en lien avec les analyses en immunologie
• Au minimum un bac en sciences biologiques avec de l\'exp\xc3\xa9rience en techniques immunologiques
• \xc3\x8atre \xc3\xa0 l\xe2\x80\x99aise dans des environnements \xc3\xa0 forte croissance
• Connaissance des bonnes pratiques de laboratoire clinique BPLC est un atout
• Exp\xc3\xa9rience dans un environnement r\xc3\xa9glement\xc3\xa9 (BPL, BPLC)
• Aptitude pour le travail minutieux, la communication et le travail en \xc3\xa9quipe dans un environnement multidisciplinaire;
• Exp\xc3\xa9rience en industrie (CRO, Biopharma ou entreprises en biotechnologies) est un atout
• Dext\xc3\xa9rit\xc3\xa9 manuelle
• Bonne ma\xc3\xaetrise du fran\xc3\xa7ais;
• Connaissances suffisantes de l\xe2\x80\x99anglais \xc3\xa9crit et parl\xc3\xa9 afin d\xe2\x80\x99\xc3\xaatre en mesure de bien comprendre les documents servant \xc3\xa0 l\xe2\x80\x99ex\xc3\xa9cution du travail et d\xe2\x80\x99interagir avec nos clients majoritairement anglophones

With unrivaled expertise in immunology, and operating sites in North America (East and West Coast) and Europe, Nexelis is a leading provider of assay development and advanced laboratory testing services in the infectious diseases, metabolic diseases, and oncology fields. Our versatile team of scientists, working with our advanced technology platforms, were instrumental in the development, qualification, validation, and large-scale sample testing of assays that supported the FDA filing of almost 100 new molecular entities, including blockbuster vaccines, anti-viral drugs, and immunotherapy, gene and cell therapy products.

We are currently looking for motivated candidates with experience to fill the Scientist positions. The Scientist will have solid expertise in virology and or bacteriology and will be responsible for performing assay development, qualification and validation of a variety of neutralization assays, including but not limited to SARS-CoV-2 and its variants.

Your main responsibilities:

• Perform the development, qualification and validation of assays to assess the immune responses to various vaccine/drug candidates including, but no limited to SARS-CoV-2 and its variants;
• Prepare qualification/validation plans and reports, procedures (analytical method) that meet written scientific standards and comply with Nexelis\xe2\x80\x99 quality assurance and operations and the client-specific requirements;
• Conduct literature searches of science/medical search engines and libraries;
• Troubleshoot technical issues related to the assays;
• Prepare presentations of scientific data for internal and external discussions;
• Provide mentoring/training over Research Associates and technical staff;
• Be compliant to all applicable regulations (e.g., GCLP) and biosafety / EHS standards;
• May interact with clients, business development, account management and operations management to support commercial proposals in terms of scientific design and lab workload assumptions.

What we are looking for:

• Solid knowledge of cell-based assays for neutralizing antibody detection;
• Solid knowledge in virology and/or bacteriology;
• Proficiency in immunoassays and/or immunogenicity-based methodologies;
• Knowledge and experience in method development and validation of immunogenicity assays;
• Knowledge of immunogenicity guidance and industry standards, eg: FDA;
• Proven leadership and management skills;
• Team player, client oriented and strong organizational skills;
• Proficient with office tools (Excel, Word, PowerPoint).
• Minimum of a B.Sc. virology / immunology or related field, M.Sc. or Ph.D. an asset;
• 2-3 years of pertinent work experience, ideally in a CRO and/or a pharmaceutical company;
• Excellent French and English, written and spoken.
• Applicants must be legally authorized to work in Canada.

Q\xc2\xb2 Solutions is a leading clinical trial laboratory services organization with end-to-end laboratory services and secure, enterprise-wide biospecimen and consent management solutions.

IQVIA