One of Canada's Top 10 Research Hospitals, Sunnybrook Research Institute is developing innovations in care for the more than 1.3 million patients the hospital cares for annually.
Sunnybrook Research Institute is the research enterprise of Sunnybrook Health Sciences Centre, a teaching hospital fully affiliated with the University of Toronto. Research spans three Toronto-based campuses, eight programs and three scientific platforms. Our main aims are to understand and prevent disease, and to develop treatments that enhance and extend life. Our vision is to invent the future of health care. Each year, we conduct about $100 million in research across 500,000 square feet, including in the world's first Centre for Research in Image-Guided Therapeutics.
Our is seeking a research software developer, at the Physical Sciences Platform & Hurvitz Brain Sciences Program, Sunnybrook Research Institute of the University of Toronto, under the supervision of .
The successful candidate will be responsible for assisting with the development, optimization and maintenance of an automated computational pipeline ( : Multi-modal Image Registration And Connectivity anaLysis), that couples MRI images with cellular information from cleared brain tissue (3D histology image with lightsheet microscopy) and the reference atlases to probe brain-wide circuit alterations across spatial scales. MIRACL enables the segmentation, registration, and analysis of histological features across the whole brain or multiple neuronal circuits, as well as along the length of specific fibre tracts. This pipeline is being used by many collaborating groups within Canada, and internationally in countries including USA, Germany, and Switzerland. Dr. Goubran's lab develops novel computational & AI tools to probe, predict and understand neuronal and vascular circuit alterations in neurological disorders, including Alzheimer's disease, stroke, and traumatic brain injury. The lab consists of a diverse, multidisciplinary team of engineers, neuroscientists, and software developers. This dynamic and collegial research environment provides opportunities to participate in pioneering AI and computational tool development that will be used to understand and treat neurological diseases. In addition to working on MIRACL, the successful candidate will assist on several ongoing projects in the lab, including the investigation of structural and functional brain connectivity and their associations with the spread of pathological proteins and cognition in Alzheimer's disease. The candidate will be expected to work independently and as a team member with investigators, staff, graduate/undergraduate students, and clinicians. There will be opportunities for contributing to publications, and presenting at/attending international conferences and workshops, focused on novel computational tools for neuroscience research and developing AI and image analysis algorithms.
Qualifications:
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