Job Description

Date Posted: 07/05/2023
Req ID:32526
Faculty/Division: Faculty of Dentistry
Department: Faculty of Dentistry
Campus: St. George (Downtown Toronto)

Description:

About us:

Exciting new advances and global challenges are radically reshaping the field of dentistry. Our vision at the Faculty of Dentistry at the University of Toronto is to not just address and respond to these changes - but to thoughtfully and conscientiously shape the field of the future.

With our robust and comprehensive educational training programs (DDS, MSc, PhD degrees, IDAPP and other specialty programs), our emphasis on community outreach and care, and our internationally known and interdisciplinary research mission, the Faculty of Dentistry at the University of Toronto continues to earn its reputation as one of the top dental schools in North America. Throughout more than 145 years of dental education -- the oldest, largest and most comprehensive training program in Canada -- we have striven to graduate the highest quality of students while providing the public the highest standards of care.

We are driving by our vision to improve health by advancing dentistry through inspired leadership, innovation, and excellence in education, research and practice.

Your Opportunity:

Professor Michael Glogauer in the Faculty of Dentistry is developing new phosphorylated lantibiotics from oral commensal microorganisms called Streptococcus salivarius. The successful candidate is expected to have significant experience in this field, including developing probiotics from oral streptococci and performing structural analysis on the produced metabolites.

https://www.dentistry.utoronto.ca/faculty-profiles/michael-glogauer

Your Responsibilities Include:

Involved in experimental design to develop phosphorylated lantibiotics into new biotherapeutics; this includes developing new methods for the production/purification of the metabolites, designing new multispecies biofilms models to test for the antibiofilm activity, and developing new immunomodulation assays involving neutrophils, macrophages, and T cells.

Essential Qualifications:

Education - Ph.D. in Microbiology with 5 years of postdoc experience in salivaricins and lantibiotics.

Experience - Demonstrated strong experience in lantibiotics and other ribosomally synthesized and post-translationally modified peptides (RiPPs) produced by oral bacteria. Candidate must have strong experience in Whole genome sequencing, multispecies biofilms, comparative genomics, metagenomics, lantibiotics structural biology, and probiotics development. Candidate must have a track record of publishing lantibiotics research in high-impact scientific journals.

Skills - Microbiology skills, oral bacteria isolation, antagonism tests, peptide extraction, HPLC, UPLC, NMR, Mass spectrometry, Confocal microscopy, Microbiome sequencing, metagenomics analysis, cloning and expression, Flow cytometry.

Other - Bioinformatics and microbiome sequencing, NMR spectroscopy, and Mass spectrometry.

This opportunity of Research Associate (Limited Term) is a 2-year term appointment, with the possibility of extension.

Closing Date: 07/14/2023,11:59PM ET
Employee Group: Research Associate
Appointment Type: Grant - Term
Schedule: Full-Time
Pay Scale Group & Hiring Zone: R01 -- Research Associates (Limited Term): $47,287 - $88,663
Job Category: Research Administration & Teaching

All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.

Diversity Statement

The University of Toronto embraces Diversity and is building a culture of belonging that increases our capacity to effectively address and serve the interests of our global community. We strongly encourage applications from Indigenous Peoples, Black and racialized persons, women, persons with disabilities, and people of diverse sexual and gender identities. We value applicants who have demonstrated a commitment to equity, diversity and inclusion and recognize that diverse perspectives, experiences, and expertise are essential to strengthening our academic mission.

As part of your application, you will be asked to complete a brief Diversity Survey. This survey is voluntary. Any information directly related to you is confidential and cannot be accessed by search committees or human resources staff. Results will be aggregated for institutional planning purposes. For more information, please see .

Accessibility Statement

The University strives to be an equitable and inclusive community, and proactively seeks to increase diversity among its community members. Our values regarding equity and diversity are linked with our unwavering commitment to excellence in the pursuit of our academic mission.

The University is committed to the principles of the Accessibility for Ontarians with Disabilities Act (AODA). As such, we strive to make our recruitment, assessment and selection processes as accessible as possible and provide accommodations as required for applicants with disabilities.

If you require any accommodations at any point during the application and hiring process, please contact .

University of Toronto