Job Description

Job Posting #: 923501

Site: Princess Margaret Research Institute

Department: Research, Notta Lab

Reports to: Principal Investigator

Hours: 37.5

Salary: $25.64 \xe2\x80\x93 $33.33 hourly: To commensurate with experience and consistent with UHN compensation policy

Status: Temporary Full-time (3 Year)

Posted Date: August 10, 2023

Closing Date: Until Filled

The University Health Network, where \xe2\x80\x9cabove all else the needs of patients come first\xe2\x80\x9d, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of \xe2\x80\x9cTransforming lives and communities through excellence in care, discovery and learning\xe2\x80\x9d, the University Health Network (UHN), Canada\xe2\x80\x99s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

Position Summary

The Notta laboratory is located at the Princess Margaret Cancer Centre (Toronto, Canada) and is associated with the Medical Biophysics program at the University of Toronto. Our research program is focussed on pancreatic cancer, one of the most aggressive tumour types in oncology. Broadly, our laboratory is interested in several aspects of the disease such as its cellular origins, mechanisms of drug resistance, and tumour evolution. Our laboratory is also part of the Pancreatic Cancer Translational Initiative (PanCuRx) at the Ontario Institute for Cancer Research. The PanCuRx Program is a translational research initiative that aims to significantly improve the lives of patients with pancreatic adenocarcinoma by generating new knowledge about genetic and biologic subsets of disease, mechanisms of tumorigenesis, and unique treatment options. Our laboratory is split between wet and dry components. On the wet-lab side, our work focuses on patient derived organoids, CRISPR, xenografting, molecular profiling, genomics and drug screening. On the dry lab side, we perform molecular subtyping of RNA-seq data (both bulk and single cell), whole genome sequencing (both bulk and single cell), statistical analysis of large datasets, data integration, tumour evolution analysis, genomic workflows for patients on clinical trial.

Projects in our lab vary widely but typically involve investigating mechanisms of pancreatic cancer development. We encourage trainees to bring their own ideas and expertise to address new problems. Trainees with a wet lab or computational background are welcomed to apply. Candidates are expected to hold a PhD, MD or both. Candidates who are close to finishing their PhDs but have not published are also encouraged to apply. All candidates should have a manuscript in preparation or have published at the time of the application. No experience in pancreatic cancer is necessary.

Additional information about the Notta Lab can be found at:
Website:
Twitter: @LabNotta

Qualifications

• Recently graduated from PhD or MD program
• Publication(s) and manuscript(s) in preparation or completed.
• Excellent organizational and analytical skills, along with a high degree of independence and flexibility to thrive in a novel and rapidly evolving research environment.
• Ability to write scientific communications and present their work
• Excellent initiative and leadership qualities

Why join UHN?

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP

) * Close access to Transit and UHN shuttle service

• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN\'s attendance management program, to be eligible for consideration.

Vaccines (COVID and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.

UHN is a respectful, caring, and inclusive workplace. We are committed to championing accessibility, diversity and equal opportunity. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known in advance. Any information received related to an accommodation will be addressed confidentially.

University Health Network thanks all applicants, however, only those selected for an interview will be contacted.

University Health Network