Job Description

Please refer to the job aid for instructions on how to apply.
If you are an active McGill employee (ie: currently in an active contract or position at McGill University), do not apply through this Career Site. Login to your McGill Workday account and apply to this posting using the Find Jobs report (type Find Jobs in the search bar).
Postdoctoral Fellow - Edema in Brain Cancer
Couturier Lab, Montreal Neurological Institute (The Neuro), McGill University
About the Project
The Couturier Lab is seeking a highly motivated Postdoctoral Fellow to join an interdisciplinary project titled "Dissecting and Targeting the Cellular Drivers of Edema in Brain Cancer."
This D2R-funded initiative investigates how the tumour microenvironment contributes to blood-brain barrier (BBB) dysfunction and edema in brain cancer, a major source of morbidity in the disease. Using radiomics, single-cell, and spatial omics, the project integrates imaging and molecular data to better understand tumour-vascular interactions and guide the development of safer, targeted therapeutic strategies for edema.
About the Lab
The Couturier Lab integrates single-cell, spatial, and imaging-based omics to deconstruct brain tumour behaviours into their cellular and molecular building blocks. Our research spans the interface of molecular biology, computational modeling, and clinical imaging, with the aim of translating mechanistic discoveries into precision strategies for patient care.
Based at The Neuro (Montreal Neurological Institute-Hospital), the lab is part of a dynamic ecosystem that bridges fundamental discovery with translational neuro-oncology.
About McGill and Montreal
Montreal is one of North America's leading centres for research and innovation, home to world-class institutions such as McGill University, The Neuro, and the Goodman Cancer Institute. The city offers an exceptional quality of life, with a vibrant cultural scene, affordable living, and a welcoming bilingual environment. Its compact layout, efficient public transit, and abundance of green spaces make Montreal an outstanding place to live and work.
Position Overview
The postdoctoral fellow will lead the computational and integrative analysis of multimodal datasets linking MRI features with transcriptomic and spatial maps of human glioblastoma.
While primarily computational, this position also involves supporting wet-lab validation using spatial transcriptomics (Visium HD) and multiplex immunofluorescence, offering a unique cross-training opportunity in experimental spatial biology.
The fellow will be expected to work efficiently as part of a multi-disciplinary team including graduate students, technicians, and clinicians from multiple fields.
Key Responsibilities
Develop and apply computational pipelines to integrate and analyze radiomic, single-cell, and spatial transcriptomic data. * Prepare figures, manuscripts, and presentations for high-impact publications.

• Mentor graduate students and assist with grant and conference submissions.

• Work closely with collaborators to align imaging, molecular, and therapeutic validation efforts.

Qualifications

• PhD in Computational Biology, Genomics, Neuroscience, Biomedical Engineering, or related field.

• Demonstrated experience with single-cell and/or spatial transcriptomic analysis (Scanpy, Seurat, Squidpy, etc.).

• Strong programming proficiency in Python and R; experience with machine-learning or radiomic tools (PyTorch, scikit-learn, nnU-Net) is highly desirable.

• Background in neurobiology, vascular biology, or glioma immunology preferred.

• Experience with MRI preprocessing and segmentation is an advantage.

• Basic experimental skills in the wet lab (e.g. RNA extraction, cryosectioning, immunostaining) are desirable.

• Evidence of independent research and peer-reviewed publications.

Excellent teamwork, communication, and organizational abilities
Compensation and Terms

• Duration: 1-year full-time appointment, renewable depending on performance and funding.

• Start date: Winter 2026 or earlier, depending on availability.

• Salary: Starting at $48,000/year, commensurate with experience, according to the

.
Why Join Us

• Contribute to a high-impact, translational project bridging radiomics, spatial biology, and RNA therapeutics.

• Access state-of-the-art equipment: 10x Visium HD and Chromium X, PhenoCycler Fusion, NextSeq 2000 and high-performance computing resources.

• Collaborate with internationally recognized leaders in computational neuro-oncology.

• Thrive in The Neuro's open-science environment, fostering data sharing and interdisciplinary innovation.

Before applying, please note that to work at McGill University, you must be both authorized to work in Canada and willing to work in the province of Quebec at the campus where the position is based / located.
McGill University is an English-language university where most teaching and research activities are conducted in the English language, thereby requiring English communication both verbally and in writing.
Annual Salary: $48,000.00
Hours per Week: 35 (Full time)
Location: Montreal Neuro.
Supervisor: Assistant Professor (Clinical)
Position Start Date: 2026-01-15
Position End Date: 2027-01-14
Deadline to Apply: 2025-11-30
McGill University hires on the basis of merit and is strongly committed to equity and diversity within its community. We welcome applications from racialized persons/visible minorities, women, Indigenous persons, persons with disabilities, ethnic minorities, and persons of minority sexual orientations and gender identities, as well as from all qualified candidates with the skills and knowledge to productively engage with diverse communities. McGill implements an employment equity program and encourages members of designated groups to self-identify. Persons with disabilities who anticipate needing accommodations for any part of the application process may contact, in confidence, .

Skills Required