Job Description

Company:


Chronic kidney disease (CKD) is a serious and growing global health challenge, affecting approximately 1 in 7 people worldwide. In the absence of effective treatments, patients may progress to kidney failure, requiring dialysis or transplantation--placing a significant burden on patients, families, and healthcare systems. While recent advances have benefited certain subsets of kidney disease patients, many common forms of CKD still lack effective therapeutic options.



Borealis was founded on the belief that the convergence of scientific and translational breakthroughs can unlock the potential of RNA therapeutics to address some of the most rare and underserved kidney diseases--and beyond. Borealis builds on the success of Chinook Therapeutics, a kidney disease company with a research site in Vancouver that was acquired by Novartis in 2023 for $3.5 billion. The Borealis team has strong leadership and academic advisors with deep experience and expertise in both kidney disease and RNA therapeutics. Headquartered in Vancouver, BC, Borealis operates state-of-the-art wet labs equipped for molecular and cellular biology, in vivo pharmacology, chemistry, DMPK, bioinformatics, and analytical sciences.





We are a creative and innovative team that strives for excellence in all we do and have fun along the way. Our core focus is on helping patients and advancing science. For more information on Borealis, check out our sites https://borealisbio.com & https://www.linkedin.com/company/borealis-biosciences-inc.

We seek applicants from all backgrounds to ensure we get the best, most innovative talent on our team. We are building a diverse and inclusive workforce - come and be a part of our growth! We strongly encourage candidates with less traditional backgrounds or those who may meet the qualifications in a different way to apply.





Position:



Borealis Biosciences is seeking an enthusiastic and collaborative contractor to join the Discovery Biology team at our laboratories situated in Vancouver, Canada. The successful candidate will perform, analyze in vitro experiments, and support the execution of the single cell RNAseq workflow. This position offers an exciting opportunity to work in an innovative and collaborative team with deep scientific experience and a focus on patients. This is a contract position (35-40 hours per week). We anticipate this position to be 1-year fixed term.





Responsibilities include:



Isolate cells/nuclei from mouse tissues Prepare sn/scRNAseq libraries for sequencing Explore in cellular systems to evaluate potency of oligonucleotides to knock-down gene targets and execute on oligo screening Support in vitro and ex vivo experiments for the advancement of platform development plan and preclinical drug discovery programs Prepare clear and concise study protocols and technical reports and maintain an accurate electronic lab notebook Participate and present data in team meetings Actively support colleagues and contribute to a collaborative work environment




Location:





This is an on-site lab-based position located in Borealis Bio's Vancouver, BC headquarters. Much of your time will be spent on conducting wet lab work.


Education, Experience, and Skills:


B.Sc. or MSc. degree in a relevant discipline with 2+ years of hands-on research experience, preferably in an industrial setting Hands-on experience in advanced molecular biology techniques (qPCR, bulk RNAseq, sn/scRNAseq Library preparation) Experience with Split-Seq workflow is a plus but not required Experience with liquid handling and automation is a plus but not required Extensive experience in cell culture is strongly preferred Strong working knowledge of cellular and molecular biology Proficient with Microsoft suite; experience with Benchling is a plus Effective time management skills and ability to thrive in a fast-paced, cross-functional team environment Comfortable with adjusting workloads based on changing priorities A strong team player with a passion for science and drug discovery
Positive attitude and high personal and ethical standards

Compensation: The hourly rate ranges from $35.00 to $45.00 per hour.






Borealis is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind. We are committed to fostering an environment where ALL people are welcome and supported. We cultivate a culture of inclusion for all employees that respects their individual strengths, views, and experiences. We believe that our differences enable us to be a better team - one that makes better decisions, drives innovation, and delivers better business results. Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect.