Job Description

Custom Biologics

has an exciting opportunity for an

Associate Scientist

that is either

MSc

trained, or

BSc

trained with 2 years of experience, to join our Bioassay Team in the Scientific Innovation and Research Division in Toronto, Canada.

Custom Biologics is a Health Canada audited, GMP-compliant, global service provider for functional testing of biotherapeutics, biosimilars and antibody drug conjugates. For over 21 years, our scientists have been designing and validating sophisticated bioanalytical assays to characterize and measure the therapeutic potential of large molecule biotherapeutics. Our work supports regulatory drug submission applications from biopharmaceutical companies globally.

We are seeking an

Associate Scientist

with expertise in protein biochemistry, cellular biology and molecular biology. Strong laboratory skills are highly preferred. The successful candidate will be a key technical contributor to thevalidation and execution of cell-based and solid phase ligand binding assays to measure the functional and affinity binding properties of biotherapeutics including therapeutic monoclonal antibodies, biosimilars, antibody drug conjugates, peptides, biologics and oncolytic viruses.

This position requires hands-on laboratory work. Familiarity with GMP/GLP regulations is desired but not a requirement.

Scientific excellence is the pillar of the Company. The ideal candidate will be joining a team of highly motivated individuals and a workplace culture driven by collaboration, achievement, quality and growth. S/he is highly motivated with a strong 'can-do' personality, excellent laboratory, critical thinking, results driven, and works well within a team to deliver excellence to our clients.

KEY DUTIES AND RESPONSIBILITIES:

Validate and execute in vitro experiments to characterize and measure the therapeutic and binding properties of biotherapeutics including monoclonal antibodies, antibody drug conjugates, biosimilars and biologics. Perform cell culture-based bioassays, immunological assays (i.e. ELISA), protein affinity binding studies (biolayer interferometry), DNA-based and other assays as required Participate in the review and interpretation of scientific literature to learn about new techniques and applications. Ensure that experiments, analytical methods and data meet the scientific and regulatory requirements for the intended use i.e. characterization, comparability, stability, and lot release. Familiarity with USP and FDA guidelines helpful but not required. Participate in the development of SOPs, study protocols, reports and other scientific documents. Maintain a steady grasp of new scientific developments and new technologies. Perform additional duties to support the safe and efficient operation of the laboratory and workplace.

SKILLS & COMPETENCIES:

Excellent interpersonal, verbal and written communication skills. A proven ability to be highly productive and successful in a high pace laboratory environment with excellent attention to details and meticulous bench work. Competency in computer skills and familiarity with Microsoft Office programs (Word, Excel, Project, PowerPoint). Excellent team player. Self-motivated and willing to support co-workers with other projects. Shares relevant information and seeks technical advice and input when necessary. Willing to accept temporary responsibilities outside of initial job description.

EDUCATION & EXPERIENCE:

An MSc in biological sciences or a BSc in biological sciences with a minimum of 2 years of demonstrated experience in developing and optimizing biological assays and protein-protein interaction studies. Expertise in mammalian cell culture and aseptic techniques. Highly familiar with standard testing equipment and procedures including, but not limited to, biolayer interferometry, ELISA, cell culture applications and cell-based bioassays, screening assays, enzymatic assays, protein affinity/binding measurements, and QPCR. Strong practical knowledge of quality statistics is desired, i.e. Parallel line analysis. A proven ability to be highly productive and successful in a high pace work environment with excellent attention to details and meticulous bench work. Competency in computer skills and familiarity with Microsoft Office programs (Word, Excel, Project, PowerPoint).

WORKING CONDITIONS

Successful candidate will be working in a controlled regulatory compliant biosafety level 2 laboratory environment and office. Work may periodically require attending to experiments outside standard working hours.

Custom Biologics is an equal opportunity employer. We thank everyone for their interest, only those candidates considered for employment will be contacted.

Job Type: Full-time

Pay: $50,000.00-$60,000.00 per year

Benefits:

Dental care Extended health care Vision care
Ability to commute/relocate:

Etobicoke, ON M9W 4Z4: reliably commute or plan to relocate before starting work (required)
Education:

Bachelor's Degree (preferred)
Work Location: In person